![Permutations of the tree rawn clark pdf](https://kumkoniak.com/23.jpg)
Five genes with scores between 1.4 and 1,490 were selected based on literature search due to the extensive investigations of their gene products in maternal blood in preeclampsia.
![permutations of the tree rawn clark pdf permutations of the tree rawn clark pdf](https://studymaterialcenter.in/wp-content/uploads/2021/05/Permutations-and-Combinations-pdf-17-1150x2048.jpg)
(A) Human microarray data on 79 human tissues and cells downloaded from the BioGPS database was used for the generation of placenta enrichment scores (placental expression/mean expression in 78 other tissues and cells). The color code depicts p-values.įigure S5: The timing of gene module dysregulation in preterm preeclampsia. The groups of most enriched biological processes were manually circled and labeled. Sizes of the circles relate to the number of genes involved in the biological processes and colors refer to p-values. (B,C) The networks of biological processes enriched among genes dysregulated in preeclampsia and co-expressed with hub factors in M1 ( ZNF554) and M2 ( BCL6) modules were visualized with the BINGO module of Cytoscape. BCL6 and ARNT2 had the most correlation with FLT1. Within the M2 (red) module, BCL6, BHLHE40, and ARNT2 transcription regulatory genes were correlated most strongly with predominantly placenta-expressed genes. ESRRG and ZNF554 had the most correlation with CSH1 and HSD11B2, genes strongly implicated in fetal growth.
![permutations of the tree rawn clark pdf permutations of the tree rawn clark pdf](https://i.stack.imgur.com/9qEB6.jpg)
Within the M1 (green) module, ESRRG, POU5F1, and ZNF554 transcription regulatory genes correlated most strongly with predominantly placenta-expressed genes. (A) Co-expression matrix of transcription regulatory genes and predominantly placenta-expressed genes in the M1 and M2 modules. Figure S1: Hub transcription regulatory genes in the M1 and M2 modules and their interaction network.
![Permutations of the tree rawn clark pdf](https://kumkoniak.com/23.jpg)